Protein name:
Gamma-glutamyltranspeptidase 1 (GGT 1) ;
Alternative:
3.4.19.13;Glutathione hydrolase 1 ) ;Gamma-glutamyltransferase 1 ;3.4.19.14;Leukotriene-C4 hydrolase ) ;
CD:
CD224 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain.
Function:
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MKKRYLLLAL | AAVALVLLIL | GLCLWLPSNS | KPHNHVYPRA | AVAADALRCS |
100:
EIGRDTLRDG | GSAVDAAIAA | LLCVGLMNAH | SMGIGGGLFL | TIYNSTTRKA |
150:
EIINAREVAP | RLASASMFNS | SEQSEEGGLS | VAVPGEIRGY | ELAHQRHGRL |
200:
PWARLFQPSI | ELASQGFPVG | KGLAAALERS | QDAIKRHPAL | CEVFCRNGNV |
250:
LREGDLVTMP | RLAKTYETLA | VEGAQAFYNG | SLTAQIVKDI | QEAGGIVTAE |
300:
DLNNYRAELI | EQPLRISLGD | AQLYAPNAPL | SGPVLALILN | ILKGYNFSRA |
350:
SVETPEQKGL | TYHRIVEAFR | FAYAKRTLLG | DPKFVNVTEV | VRNMSSEFFA |
400:
DQLRARISDT | TTHPDSYYEP | EFYTPDDAGT | AHLSVVSDDG | SAVSATSTIN |
450:
LYFGSKVRSR | ISGILFNDEM | DDFSSPNITN | QFGVRPSPAN | FITPGKQPLS |
500:
SMCPVIIVGE | DGQVRMVVGA | SGGTQITTST | ALAIIHSLWF | GYDVKRAVEE |
550:
PRLHNQLLPN | TTTLEKGIDQ | AVAAALKTRH | HYIQDASTFI | GVVQAIVRTP |
568:
SGWAAASDSR | KGGEPAGY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Polyclonal Antibody for Pig GGT 1
Polyclonal Antibody for Pig GGT 1
Polyclonal Antibody for Pig GGT 1
Polyclonal Antibody for Pig GGT 1
Monoclonal Antibody for Pig GGT 1
Monoclonal Antibody for Pig GGT 1
Monoclonal Antibody for Pig GGT 1
Monoclonal Antibody for Pig GGT 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-18
tissue :
Brain capillary .
2.
"Sequences and genetic variations of fourty-four porcine coat color related genes."
Okumura N.
,
Matsumoto T.
,
Hamasima N.
,
Uenishi H.
,
Ogawa T.
,
Komatsuda A.
,
Fukudome N.
,
Ide H.
,
Suzuki A.
,
Kojima C.
,
Awata T.
Submitted (2006-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GENE ORGANIZATION;ALTERNATIVE PROMOTER USAGE